Research Associate I - Nucleic Acid Processing for Genomics Assays (REQ1153)

Compensation

: $74,605.00 - $117,740.00 /year *

Employment Type

: Full-Time

Industry

: Scientific Research



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Research Associate I - Nucleic Acid Processing for Genomics Assays

Job ID: req1153
Employee Type: exempt full-time
Facility: Frederick: Ft Detrick
Location: PO Box B, Frederick, MD 21702 USA

The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc. The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases.

Our core values of accountability, compassion, collaboration, dedication, integrity, and versatility serve as a guidepost for how we do our work every day in serving the public's interest.

Position Overview:

PROGRAM DESCRIPTION

The Molecular Characterization Laboratory (MoCha) is part of Leidos Biomedical Research's Clinical Research Directorate (CRD) at the Frederick National Laboratory for Cancer Research. The MoCha Laboratory is responsible for providing high-level research in support of the NCI-Cancer Diagnostics Program (CDP) within the Division of Cancer Treatment and Diagnosis (DCTD). MoCha is charged with the development and application of genomic assays for use in medical research and diagnostics for DCTD-sponsored national extramural clinical trials.

The Molecular Characterization Laboratory (MoCha) focuses on development and application of novel genomic assays for clinical applications.

KEY ROLES/RESPONSIBILITIES

The Research Associate I will perform nucleic acid extraction, nucleic acid QC, specimen accessioning and tracking to facilitate cutting edge genomic research in support of DCTD projects e.g. Patient Derived Xenograft Models (PDM) project, genomic characterization of patient samples enrolled in clinical trials.

Responsibilities:
  • Performs nucleic acid extractions manually and using automated platforms
  • Performs quality and quantitation assays on extracted nucleic acids in high throughput assay platforms
  • Accessions and tracks biospecimens from multiple projects
  • Performs appropriate dilutions of the extracted nucleic acids for downstream genomic assays using automated platforms
  • Recommends and optimizes new nucleic acid QC assay platforms
  • Recommends and optimizes biospecimen tracking processes
  • Develops new assays and applies the methods/assays utilizing sound scientific judgement
  • Develops and maintains SOPs for above-mentioned research activities
  • Performs formal reporting of research data, including presentations and/or scientific publications
  • Makes detailed observations, analyzes data and interprets results
  • Investigates, creates and develops new methods and technologies for project advancement
  • Will be key staff member for above-mentioned activities
  • Maintains high level of professional expertise through familiarity with scientific literature and presentations
  • Maintains essential laboratory supplies and monitors equipment for optimum performance
  • May participate in scientific conferences and contribute to scientific journals
  • May train in and perform next generation sequencing assays
  • May participate in assay development projects

This position will be located in Frederick, Maryland.

BASIC QUALIFICATIONS

To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:

  • Possession of a Bachelor's degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) or four (4) years of experience in lieu of degree. Foreign degrees must be evaluated for U.S. equivalency
  • A minimum of two (2) years of relevant experience
  • Strong technical skills in molecular assays and/or nucleic acid extraction and understanding of QC metrics of nucleic acids
  • Ability to independently evaluate the suitability and quality control of research or production assays or tests, develop and follow SOPs, and analyze and report data
  • Ability to track information in a large cohort of samples and monitor progress of multiple projects
  • Adequate computer skills to document, organize, and present experimental data
  • Strong critical thinking, problem solving, organizational and multitasking skills
  • Ability to communicate effectively, both verbally and in writing
  • Ability to work effectively in a matrix and team-oriented environment
  • This position is subject to obtaining and maintaining a security clearance

PREFERRED QUALIFICATIONS

Candidates with these desired skills will be given preferential consideration:
  • Experience with automated nucleic acid extraction platforms
  • Experience with liquid handling automation platforms (sample dilution robotic platforms)
  • Familiarity with clinical oncology studies and other protocol-driven clinical research

JOB HAZARDS
  • This position is subject to working with or have potential for exposure to animal(s) and/or animal material(s)
  • This position is subject to working with or have potential for exposure to infectious material, requiring medical clearance and immunizations


Equal Opportunity Employer (EOE) | Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace (DFW)

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Associated topics: amp, anatomic, companion, diagnostics, forensic, investigative, lab, laboratory, molecular, pathology * The salary listed in the header is an estimate based on salary data for similar jobs in the same area. Salary or compensation data found in the job description is accurate.

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