• Flagship Pioneering
  • $94,410.00 -169,240.00/year*
  • Cambridge , MA
  • Scientific Research
  • Full-Time
  • 101 Auburn St

Company SummaryVL56, Inc. is a privately held, early-stage biotechnology company that is pioneering computational protein design. VL56 was founded by Flagship Pioneering, a team of entrepreneurial scientists that conceives, creates, resources, and grows first-in-category life sciences companies. Since 2000, Flagship has created over 75 groundbreaking companies that are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna Therapeutics (MRNA), Seres Therapeutics (MCRB), Syros Pharmaceuticals (SYRS), Rubius Therapeutics (RUBY), Evelo Biosciences (EVLO), and Kaleido Biosciences (KLDO).Position SummaryWe are seeking a motivated and talented Research Associate with experience in molecular biology and protein expression to spearhead the in-house production of recombinant candidate proteins. The successful candidate will work with and support our scientists in a dynamic, fast-paced environment to validate our proprietary design platform and rapidly advance our technology.Key ResponsibilitiesDesign and construct expression plasmidsProduce and purify proteins from mammalian, bacterial, and/or yeast culture systems as appropriateWork independently to design, interpret and troubleshoot experiments and communicate results to the team Depending on candidate interest, experience and project priorities, the individual may also assist in the development and execution of a variety of biochemical/biophysical and functional in vitro assays to characterize candidate proteinsExperience and QualificationsB.S or M.S. in Bioengineering, Chemical Engineering, Biochemistry or similar field with a minimum of 2 years biotech/pharma industry experience required.Facility with basic molecular biology and cloning techniques including PCR, ligation and ligation independent cloning requiredExperience with protein expression from transient mammalian cultures and/or bacteria; protein purification by affinity chromatography, SEC, etc. Familiarity with protein characterization techniques (SDS-PAGE, Western Blot, biochemical assays such as ELISA, etc.)Ability to work with minimal supervision to design experiments, interpret data and troubleshoot problemsAttention to detail, ability to multi-task, and strong communication skills are required

Associated topics: aseptic, bacteria, bioinformatics, biostatistics, genome, immunobioengineering, metabolism, microbiology, physical, stem cell

* The salary listed in the header is an estimate based on salary data for similar jobs in the same area. Salary or compensation data found in the job description is accurate.

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