Senior Staff Associate-LCMS.

Compensation

: $86,310.00 - $138,710.00 /year *

Employment Type

: Full-Time

Industry

: Scientific Research



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Biomarkers Core Laboratory at the Irving Institute for Clinical and Translational Research is seeking a staff associate/senior staff associate with expertise in the field of untargeted metabolomics, mass spectrometry and related data processing and bioinformatics. This position will involve LC-HRMS and GC-HRMS profiling of endogenous and exogenous metabolites in support of precision medicine metabolomics. The ideal candidate will have a strong background in biological mass spectrometry with technical expertise in untargeted analysis and processing workflows for high-resolution mass spectrometry data sets. Minimum Qualifications :. A minimum of 3 years of professional experience in high-resolution mass spectrometry is required. A master's degree or higher is preferred. Essential Duties and Responsibilities :. Establish and develop LC and GC-MS workflows for untargeted metabolomics. Develop and customize sample preparation protocols for complex biological matrices. Preparation and analysis of samples with both LC-HRMS and GC-HRMS Thermo Orbitrap analyzers. Develop and implement bioinformatic workflows for data extraction, feature identification, and OMICS data analysis. Operate and maintain mass spectrometry instruments including the GC/LC Thermo Orbitrap MS platforms. Prepare data reports and standard operating procedure documentation. Interact with investigator clients to support sample management, study design, and data interpretation. Preferred qualifications:. Hands-on expertise in operating, maintaining and troubleshooting Thermo Q-Exactive HFX LC/MS and GC hybrid quadrupole-Orbitrap. Experience in conductinglarge scale unbiased metabolomics studies (design, sample preparation, QC monitoring, data analysis, and reporting). Expertise in various metabolite extraction techniques from biological tissues and other matrices. Demonstrated experience in applying bioinformatics and statistical software tools and suites to large untargeted metabolomics datasets. Experience in setting up well-validated targeted MRM based LCMS assays for small molecule analysis is desired. Excellent communication and interpersonal skills. Ability to maintain effective working relationships with supervisors, researchers, staff and other personnel. The compensation is commensurate with experience. Please contact ...@cumc.columbia.edu for more information. * The salary listed in the header is an estimate based on salary data for similar jobs in the same area. Salary or compensation data found in the job description is accurate.

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