• Apex Systems
  • $80,505.00 -128,560.00/year*
  • Cambridge , MA
  • Scientific Research
  • Full-Time
  • 101 Auburn St

Job Description


Research Associate, Senior Research Associate, Immuno-Oncology Discovery, 992609
Job Scope & Purpose:
Our Cambridge based client, focused in gene therapy, grounded in immune-oncology, is seeking an exceptional researcher to join their discovery team. This researcher will perform experiments using cellular and molecular immunological assays to interrogate target biology, therapeutic mechanisms of action of lead compounds, and to support I-O biomarker discovery efforts. The successful candidate will work as part of the Immuno-Oncology team to support the expansion of our immuno-epigenetic discovery programs and preclinical/clinical pipelines. Apply now to learn more!
Primary Job Responsibilities:
  • Coordinate and execute cell-based immunoassays to characterize the mechanism of action and activity of small molecule drugs designed to enhance anti-tumor immunity by targeting cancer and/or immune cells
  • Perform QC functions, instrument daily start-ups/performance monitoring, and scheduled maintenance. Maintain inventories of cell lines and primary tissue samples
  • As a member of drug discovery cross-functional teams, you will set-up and validate new ex vivo and in vivo disease models, and cell-based assays within a project scope
  • Acquire/analyze data, report the data and troubleshoot for problems in experiments. Present study results at group meetings. Track and report study progress and status with oversight from a supervisor and/or project leader
  • Prepare initial technical reports, SOPs and experimental protocols, specification/batch records
  • Provide project working groups with technical advice and problem troubleshooting related to methods, procedures, instrumentation issues, and suggest process changes to meet objectives

  • Primary Job Requirements:
  • Master s or Bachelor s degree in a life science field with a minimum of 3 years (for MS) or 6 years (for BS) of relevant laboratory experience
  • Industry experience with knowledge of the drug discovery process considered a plus
  • Passionate and proficient in in vitro and ex vivo phenotypical/functional immune cell-based assays and anti-cancer drug screens
  • Demonstrated experience in human and mouse immunology, including familiarity with I-O animal models and hands-on experience in multiparameter flow cytometry, ex vivo primary/immune cell isolation and culture, and tumor-infiltrating lymphocyte profiling
  • Expertise in T cell, dendritic cell, and macrophage biology is preferred
  • Experience with MS Office and data analysis software such as FlowJo and GraphPad Prism
  • Prior experience with any of the following assays is preferred: multiplex assays, PDX models, human blood and tumor tissue/tumor cell implant processing

  • About Stratacuity:
    Whether you are seeking a career change or simply interested in becoming part of our network, you will appreciate the ethics guiding each Stratacuity team member. We build lasting relationships with exceptional biopharmaceutical talent and take great care to protect your personal information. Upon receiving your inquiry, you may be directly contacted by a Stratacuity team member to discuss your career goals. We will not share your information with anyone without your direct prior consent.
    PROVEN SCIENTIFIC PLACEMENT
    Stratacuity is an Equal Employment Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. Stratacuity will consider qualified applicants with criminal histories in a manner consistent with the requirements of applicable law. If you have visited our website in search of information on employment opportunities or to apply for a position, and you require an accommodation in using our website for a search or application, please contact us.
    ...@stratacuity.com
    ...@stratacuity.com
    ...@stratacuity.com
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    EEO Employer
    Apex Systems is an equal opportunity employer. We do not discriminate or allow discrimination on the basis of race, color, religion, creed, sex (including pregnancy, childbirth, breastfeeding, or related medical conditions), age, sexual orientation, gender identity, national origin, ancestry, citizenship, genetic information, registered domestic partner status, marital status, disability, status as a crime victim, protected veteran status, political affiliation, union membership, or any other characteristic protected by law. Apex will consider qualified applicants with criminal histories in a manner consistent with the requirements of applicable law. If you have visited our website in search of information on employment opportunities or to apply for a position, and you require an accommodation in using our website for a search or application, please contact our Employee Services Department at 844-###-####-6178.

    Associated topics: antibody, drug development, healthcare, immuno oncology, kinesiology, microbiology, patient, physiologist, toxicologist, transfection

    * The salary listed in the header is an estimate based on salary data for similar jobs in the same area. Salary or compensation data found in the job description is accurate.

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